• Keneitsino Lydia
• June 5, 2026

Expert Carcinoma and Sarcoma MCQs with Answers – Proven Practice for Class 12 Biology

Carcinoma and Sarcoma MCQs with Answers is an important biology topic for aspirants who want to understand cancer classification, tumour origin, abnormal cell growth, metastasis, diagnosis, and treatment in a clear and exam-focused way. Carcinoma and Sarcoma MCQs with Answers helps aspirants revise the difference between cancers that arise from epithelial tissues and cancers that arise from connective tissues. In Class 12 Biology and competitive exams, cancer-based concepts are often tested through tissue origin, tumour behaviour, risk factors, and treatment methods. Through Carcinoma and Sarcoma MCQs with Answers, aspirants can build a strong foundation in human health and disease while also improving their ability to recognise key cancer-related terms.

Carcinoma and Sarcoma MCQs with Answers becomes easier when aspirants first understand carcinoma. Carcinoma is a malignant tumour that originates from epithelial tissues. Epithelial tissues form the covering of the skin, line internal organs, and make up many glands. The value of Carcinoma and Sarcoma MCQs with Answers lies in helping aspirants remember that carcinomas are among the most common types of cancer. Examples may include cancers of the skin, lungs, breast, colon, cervix, prostate, and other organs lined by epithelial cells. Carcinoma and Sarcoma MCQs with Answers also helps aspirants connect carcinoma with terms such as malignant growth, invasion, metastasis, biopsy, radiation therapy, chemotherapy, and immunotherapy.

Carcinoma and Sarcoma MCQs with Answers also explains sarcoma, which is a cancer that arises from connective tissues. Connective tissues include bone, cartilage, muscle, fat, fibrous tissue, and blood vessels. Carcinoma and Sarcoma MCQs with Answers is useful because aspirants often confuse carcinoma and sarcoma, even though their tissue origins are different. Sarcomas are generally less common than carcinomas, but they are important in biology exams because they clearly show how cancer classification depends on the origin of the affected tissue. Carcinoma and Sarcoma MCQs with Answers helps aspirants remember that osteosarcoma arises from bone, chondrosarcoma from cartilage, liposarcoma from fat tissue, and fibrosarcoma from fibrous connective tissue.

Carcinoma and Sarcoma MCQs with Answers should also be studied along with the concept of benign and malignant tumours. A benign tumour usually remains localized and does not spread to other parts of the body. A malignant tumour grows aggressively, invades nearby tissues, and may spread through blood or lymph. This spreading ability is called metastasis. Carcinoma and Sarcoma MCQs with Answers helps aspirants understand why metastasis is considered one of the most dangerous characteristics of cancer. Carcinoma and Sarcoma MCQs with Answers also supports revision of contact inhibition, which is present in normal cells but lost in cancer cells, allowing uncontrolled growth.

Carcinoma and Sarcoma MCQs with Answers is important for understanding causes and risk factors of cancer. Cancer may be caused by mutations, carcinogenic chemicals, radiation, viruses, smoking, alcohol, industrial pollutants, genetic predisposition, and lifestyle factors. Carcinoma and Sarcoma MCQs with Answers helps aspirants connect specific causes with specific cancers, such as Human Papilloma Virus with cervical cancer, aromatic amines with urinary bladder cancer, vinyl chloride with liver cancer, and tobacco smoke with lung cancer. Carcinoma and Sarcoma MCQs with Answers also teaches that oncogenes are cancer-causing genes that may develop from proto-oncogenes when normal regulation of cell division is disturbed.

Diagnosis and treatment are also key areas in Carcinoma and Sarcoma MCQs with Answers. Cancer diagnosis may involve physical examination, biopsy, blood tests, tumour markers, CT scan, MRI, PET scan, and histopathological study. Carcinoma and Sarcoma MCQs with Answers helps aspirants understand that carcinoma and sarcoma may require different diagnostic and treatment approaches depending on their location, stage, and tissue type. Treatment may include surgery, chemotherapy, radiation therapy, immunotherapy, targeted therapy, or a combination of methods. Carcinoma and Sarcoma MCQs with Answers also reminds aspirants that rapidly dividing cancer cells are more sensitive to radiation and chemotherapy, but normal rapidly dividing cells may also be affected.

For effective preparation, Carcinoma and Sarcoma MCQs with Answers should be revised through short notes, comparison tables, flowcharts, and tissue-origin charts. Aspirants can prepare a simple table comparing carcinoma, sarcoma, leukemia, and lymphoma. Carcinoma and Sarcoma MCQs with Answers becomes more useful when aspirants connect carcinoma with epithelial tissues and sarcoma with connective tissues. Aspirants should also revise related terms such as neoplasm, tumour, benign, malignant, metastasis, oncogene, carcinogen, biopsy, radiation therapy, and chemotherapy.

Carcinoma and Sarcoma MCQs with Answers:

1. Electron beam therapy is a kind of radiation therapy to treat

A. Enlarged prostate gland
B. Gall bladder stones by breaking them
C. Certain types of cancer
D. Kidney stones

Answer: C. Certain types of cancer

Explanation: Electron beam radiotherapy is a treatment that uses a radiation beam of particles called electrons. This radiation is strong enough to kill cancer cells but does not penetrate deeply beyond the surface of the skin.

2. Which of the following are symptoms of radiation disease?

A. Red and ulcerated skin
B. Nausea and loss of hair
C. Nausea and anaemia
D. Ulcerated skin, anaemia, nausea and loss of hair

Answer: D. Ulcerated skin, anaemia, nausea and loss of hair

Explanation: Radiation disease may cause symptoms such as ulcerated skin, anaemia, nausea, vomiting, diarrhoea, fatigue, fever, bleeding, and hair loss.

3. Which property do normal cells possess that is absent in cancer cells, leading to uncontrollable growth?

A. Contact inhibition
B. Rapid cell division
C. Mutation
D. Metastasis

Answer: A. Contact inhibition

Explanation: Normal cells show contact inhibition, which prevents uncontrolled growth. Cancer cells lose this property and continue dividing uncontrollably.

4. What are the genes involved in cancer known as?

A. Cancer gene
B. Oncogenes
C. Tumour genes
D. Regulator genes

Answer: B. Oncogenes

Explanation: Genes involved in cancer are known as oncogenes. These genes can promote uncontrolled cell division when activated abnormally.

5. What is cancer caused by?

A. Uncontrolled growth of tissues
B. Old age
C. Controlled division of tissues
D. None of these

Answer: A. Uncontrolled growth of tissues

Explanation: Cancer is caused by uncontrolled growth and division of abnormal cells.

6. Which cancer is a marker for AIDS/HIV patients?

A. Squamous cell carcinoma
B. Retinoblastoma
C. Kaposi’s sarcoma
D. Leukaemia

Answer: C. Kaposi’s sarcoma

Explanation: Kaposi’s sarcoma is commonly associated with AIDS/HIV patients and is considered an important marker condition.

7. What is skin cancer that forms in melanocytes called?

A. Carcinoma
B. Sarcoma
C. Melanoma
D. Adenoma

Answer: C. Melanoma

Explanation: Melanoma is a type of skin cancer that develops from melanocytes, the pigment-producing cells of the skin.

8. Assertion: The phenomenon where tumor cells detach and migrate to other parts of the body where they give rise to secondary tumors is called metastasis.
   Reason: Abnormal antigens on the surface of cells and unusual number of chromosomes cause metastasis.

A. Both Assertion and Reason are true and Reason is the correct explanation of Assertion
B. Both Assertion and Reason are true but Reason is not the correct explanation of Assertion
C. Assertion is true but Reason is false
D. Assertion is false but Reason is true

Answer: A. Both Assertion and Reason are true and Reason is the correct explanation of Assertion

Explanation: The spread of cancer cells from the original site to other parts of the body is called metastasis.

9. What are HeLa cells used in cell biology derived from?

A. Cancerous cells grown in cancer research laboratory
B. Cervical cancer cell derivatives
C. Both A and B
D. None of the above

Answer: C. Both A and B

Explanation: HeLa cells are derived from cervical cancer cells and are widely used in cancer and cell biology research.

10. How do cancerous cells spread in the body?

A. Lymph
B. Blood
C. Secondary growth of malignant tumor
D. All of the above

Answer: D. All of the above

Explanation: Cancerous cells can spread through blood, lymph, and by forming secondary malignant growths in other parts of the body.

11. Which of the following is not a type of cancer?

A. Leukemia
B. Trachoma
C. Carcinoma
D. Sarcoma

Answer: B. Trachoma

Explanation: Trachoma is an infectious eye disease caused by bacteria. It is not a type of cancer.

12. Why can cancerous cells be easily destroyed by radiation?

A. Rapid cell division
B. Lack of nutrition
C. Fast mutation
D. Lack of oxygen

Answer: A. Rapid cell division

Explanation: Cancerous cells divide rapidly, making them more sensitive to radiation damage.

13. What does carcinoma refer to?

A. Malignant tumors of the connective tissue
B. Malignant tumors of the skin or mucous membrane
C. Malignant tumors of the colon
D. Benign tumors of the connective tissue

Answer: B. Malignant tumors of the skin or mucous membrane

Explanation: Carcinoma refers to malignant tumors arising from epithelial tissues, including skin and mucous membranes.

14. Which of the following is used in the treatment of thyroid cancer?

A. I-131
B. U-238
C. Ra-224
D. C-14

Answer: A. I-131

Explanation: Radioactive iodine, I-131, is used in the treatment of thyroid cancer because thyroid cells absorb iodine.

15. Leukaemia is caused by

A. Ca-40
B. Sr-90
C. Caesium
D. Iodine

Answer: B. Sr-90

Explanation: Strontium-90 can deposit in bones and bone marrow and may increase the risk of leukaemia and bone cancer.

16. Smoking addiction is harmful because it produces polycyclic aromatic hydrocarbons, which cause

A. Reduction in oxygen transport
B. Increase in blood pressure
C. Cancer
D. Retardation of growth of foetus

Answer: C. Cancer

Explanation: Polycyclic aromatic hydrocarbons produced during smoking are carcinogenic and may damage DNA, increasing the risk of cancer.

17. Assertion: α-interferons are used in treatment of cancer.
    Reason: α-interferons provoke the immune system to identify tumor cells.

A. Both Assertion and Reason are true and Reason explains Assertion
B. Both Assertion and Reason are true but Reason cannot explain Assertion
C. Only Assertion is correct but not Reason
D. Both Assertion and Reason are wrong

Answer: A. Both Assertion and Reason are true and Reason explains Assertion

Explanation: α-interferons are used in some cancer treatments because they stimulate immune cells to attack tumor cells.

18. Fibroid, leiomyoma, uterus is a

A. Benign tumor of uterus
B. Cancer of hypothalamus
C. Tumor of cervix epithelium
D. Cancer of vaginal epithelium

Answer: A. Benign tumor of uterus

Explanation: Uterine fibroids, also called leiomyomas, are non-cancerous benign tumors of the uterus.

19. Characteristic of cancer is

A. All tumors are cancers
B. Cancers show metastasis
C. Cancerous cells show property of contact inhibition
D. All viruses are oncogenic

Answer: B. Cancers show metastasis

Explanation: Malignant cancers can show metastasis, meaning cancer cells spread from the primary site to other parts of the body.

20. A metastatic cancerous tumor is termed sarcoma if the disorder is in

A. Fibroblasts
B. Circulatory system
C. Immune system
D. Epithelial cells

Answer: A. Fibroblasts

Explanation: Sarcoma is cancer of connective tissues such as fibrous tissue, muscle, bone, or cartilage. Fibroblasts are connective tissue cells.

21. Which of the following statements is not true for cancer cells in relation to mutations?

A. Mutations inhibit production of telomeres
B. Mutations in proto-oncogenes accelerate the cell cycle
C. Mutations destroy telomerase inhibitor
D. Mutations inactivate the cell control

Answer: A. Mutations inhibit production of telomeres

Explanation: Cancer cells often maintain telomeres through telomerase activity, helping them divide repeatedly. Inhibition of telomere production is not a typical feature of cancer cells.

22. Which of the following statements is correct regarding malignant tumors?

A. Malignant tumors may exhibit metastasis
B. Patients who have undergone surgery are given cannabinoids used to relieve pain
C. Patients who have undergone surgery are given cannabinoids to relieve pain
D. Heroin accelerates body functions

Answer: A. Malignant tumors may exhibit metastasis

Explanation: Malignant tumors are cancerous and may spread to distant parts of the body through metastasis.

23. What is the name of epithelial cancer?

A. Sarcoma
B. Carcinoma
C. Leukemia
D. Lymphoma

Answer: B. Carcinoma

Explanation: Cancer arising from epithelial tissues is called carcinoma.

24. Continuous exposure to vinyl chloride may cause cancer of the

A. Liver
B. Spleen
C. Vagina
D. Prostate gland

Answer: A. Liver

Explanation: Vinyl chloride exposure is associated with liver cancer, especially angiosarcoma of the liver.

25. What is the reason for lung cancer?

A. Coal mining
B. Calcium fluoride
C. Cement factory
D. Bauxite mining

Answer: C. Cement factory

Explanation: Exposure to cement dust has been linked with respiratory problems and may increase lung cancer risk.

26. Which of the following is one of the direct causes of cancer?

A. Obesity
B. Inadequate O₂ supply
C. Atherosclerosis
D. Hypertension

Answer: A. Obesity

Explanation: Obesity is considered a risk factor for several types of cancer.

27. Why are certain tumors called malignant?

A. They are confined to specific locations
B. They invade and damage surrounding tissues
C. They show contact inhibition
D. They are not neoplastic

Answer: B. They invade and damage surrounding tissues

Explanation: Malignant tumors invade nearby tissues and can spread to distant body parts.

28. Which of the following is not a correct pair of type of cancer and origin place?

A. Benign tumor – Non-cancerous tumor
B. Carcinomas – Cancer of epithelial tissue
C. Lymphomas – Hematopoietic cells tumor
D. Sarcomas – Cancer of glands, secretory tissues

Answer: D. Sarcomas – Cancer of glands, secretory tissues

Explanation: Sarcomas arise from connective tissues such as bone, cartilage, muscle, or fibrous tissue, not from glands.

29. Chemotherapy and immunotherapy are used to destroy cancer cells that might have moved to parts of the body. What is the reason for hair loss during chemotherapy?

A. Both A and R are correct and R is the correct explanation of A
B. Both A and R are correct and R is not the correct explanation of A
C. A is correct but R is wrong
D. A is wrong but R is correct

Answer: B. Both A and R are correct and R is not the correct explanation of A

Explanation: Chemotherapy targets rapidly dividing cells. Since hair follicle cells also divide rapidly, they may be damaged, causing hair loss.

30. Which feature do cancer cells not exhibit?

A. They are not joined by cadherins
B. They do not exhibit contact inhibition
C. They exhibit metastasis
D. They undergo programmed cell death

Answer: D. They undergo programmed cell death

Explanation: Cancer cells generally avoid programmed cell death, or apoptosis, allowing them to survive and multiply abnormally.

 

Conclusion on Carcinoma and Sarcoma MCQs with Answers

In conclusion, Carcinoma and Sarcoma MCQs with Answers is a valuable study topic for aspirants preparing for Class 12 Biology, NEET, nursing, medical entrance, and other competitive exams. Carcinoma and Sarcoma MCQs with Answers improves understanding of cancer origin, tumour types, metastasis, diagnosis, treatment, and prevention. Carcinoma and Sarcoma MCQs with Answers also helps aspirants avoid confusion between epithelial cancers and connective tissue cancers. With consistent revision, Carcinoma and Sarcoma MCQs with Answers can help aspirants answer cancer-related biology questions with better accuracy, speed, and confidence.